Hsien-Te Chen Selected Research

BL-038

9/2016

BL-038, a Benzofuran Derivative, Induces Cell Apoptosis in Human Chondrosarcoma Cells through Reactive Oxygen Species/Mitochondrial Dysfunction and the Caspases Dependent Pathway.

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Hsien-Te Chen Research Topics

Disease

15	Chondrosarcoma 11/2021 - 04/2009
13	Neoplasm Metastasis (Metastasis) 11/2021 - 04/2009
12	Neoplasms (Cancer) 11/2021 - 04/2009
5	Pain (Aches) 01/2022 - 02/2010
5	Osteoarthritis 01/2021 - 04/2011
4	Discitis 01/2022 - 01/2015
4	Intervertebral Disc Displacement (Herniated Disc) 01/2021 - 01/2011
3	Spinal Cord Compression 09/2015 - 07/2007
2	Carcinogenesis 01/2016 - 04/2009
2	Cicatrix (Scar) 01/2011 - 06/2009
2	Low Back Pain (Lumbago) 08/2010 - 02/2010
1	Ankylosis 01/2022
1	Hip Dislocation 01/2021
1	Arthritis (Polyarthritis) 01/2021
1	AIDS-Related Complex (ARC) 01/2021
1	Intervertebral Disc Degeneration 01/2021
1	Hip Osteoarthritis (Coxarthrosis) 01/2021
1	Spinal Stenosis (Stenosis, Spinal) 11/2020
1	Congenital Abnormalities (Deformity) 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2019
1	Ischemic Stroke 10/2018
1	Abscess 04/2018
1	Coinfection 04/2018
1	Thyroid Neoplasms (Thyroid Cancer) 01/2018
1	Osteoporosis 01/2018
1	Bone Neoplasms (Bone Cancer) 10/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 09/2016
1	Osteosarcoma (Osteogenic Sarcoma) 01/2016
1	Lymphatic Metastasis 01/2016
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2015
1	Osteoporotic Fractures 05/2015
1	Breast Neoplasms (Breast Cancer) 05/2015

Drug/Important Bio-Agent (IBA)

6	NF-kappa B (NF-kB)IBA 06/2010 - 04/2009
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2017 - 03/2013
5	Matrix Metalloproteinases (MMPs)IBA 09/2016 - 05/2009
4	Integrin alphaVbeta3IBA 10/2009 - 04/2009
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 04/2018
3	AdiponectinIBA 08/2021 - 01/2014
3	Proteins (Proteins, Gene)FDA Link 09/2016 - 05/2009
3	CytokinesIBA 11/2012 - 04/2009
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2009 - 05/2009
2	LeptinIBA 08/2021 - 04/2009
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 04/2011
2	SolutionsIBA 11/2020 - 01/2019
2	CC ChemokinesIBA 11/2014 - 08/2009
2	Chemokine CCL5IBA 11/2014 - 08/2009
2	U 0126 (UO 126)IBA 10/2009 - 05/2009
2	Monoclonal AntibodiesIBA 10/2009 - 05/2009
2	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 10/2009 - 05/2009
2	Peptides (Polypeptides)IBA 10/2009 - 05/2009
2	arginyl-glycyl-aspartic acidIBA 10/2009 - 05/2009
2	IntegrinsIBA 05/2009 - 04/2009
1	C-Reactive ProteinIBA 01/2022
1	Nerve Growth Factor (NGF)IBA 11/2021
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 11/2021
1	AdipokinesIBA 08/2021
1	Transcription Factors (Transcription Factor)IBA 08/2021
1	ResistinIBA 08/2021
1	Nicotinamide PhosphoribosyltransferaseIBA 08/2021
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 08/2021
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 08/2021
1	Monoamine Oxidase (MAO)IBA 01/2021
1	titanium dioxide (Titania)FDA Link 01/2021
1	Sevoflurane (Ultane)FDA LinkGeneric 01/2020
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2019
1	LigandsIBA 01/2019
1	Angiopoietin-2IBA 01/2019
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2018
1	Endothelin-1 (Endothelin 1)IBA 10/2016
1	Vasoconstrictor AgentsIBA 10/2016
1	AMP-Activated Protein KinasesIBA 10/2016
1	benzofuranIBA 09/2016
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 09/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2016
1	CaspasesIBA 09/2016
1	BL-038IBA 09/2016
1	Cytochromes c (Cytochrome c)IBA 09/2016
1	Caspase 3 (Caspase-3)IBA 09/2016
1	Caspase 9IBA 09/2016
1	erucylphosphocholineIBA 01/2016
1	MitogensIBA 01/2016
1	Chemokine CCL3IBA 01/2016
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2016
1	Vascular Endothelial Growth Factor CIBA 01/2016
1	Tamoxifen FDA LinkGeneric 05/2015
1	Dihydrotachysterol (AT 10)IBA 05/2015

Therapy/Procedure

4	Decompression 11/2020 - 01/2011
3	Drug Therapy (Chemotherapy) 08/2021 - 09/2016
3	Diskectomy (Discectomy) 01/2021 - 01/2011
3	Palliative Care (Palliative Therapy) 09/2015 - 07/2007
2	General Anesthesia 01/2020 - 01/2011
2	Vertebroplasty 01/2017 - 03/2012
2	Radiotherapy 10/2016 - 09/2016
2	Therapeutics 10/2014 - 08/2010
1	Arthrodesis 01/2022
1	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2021
1	Laminectomy 11/2020
1	Minimally Invasive Surgical Procedures 01/2019
1	Pedicle Screws 01/2019